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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.