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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Vaccines cause herd immunity. If the majority of people in a community have been vaccinated against a disease, an unvaccinated person is less likely to get the disease since others are less likely to become sick from it and spread the disease.
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Asthma cases in Americans are about 75% higher today than they were in 1980.