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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
Certain topical medications such as clotrimazole and betamethasone are not approved for use in children younger than 12 years of age. They must be used very cautiously, as directed by a doctor, to treat any child. Children have a much greater response to topical steroid medications.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
It is difficult to obtain enough calcium without consuming milk or other dairy foods.
Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.

