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In 1864, the first barbiturate (barbituric acid) was synthesized.
Your skin wrinkles if you stay in the bathtub a long time because the outermost layer of skin (which consists of dead keratin) swells when it absorbs water. It is tightly attached to the skin below it, so it compensates for the increased area by wrinkling. This happens to the hands and feet because they have the thickest layer of dead keratin cells.
It is difficult to obtain enough calcium without consuming milk or other dairy foods.
Anti-aging claims should not ever be believed. There is no supplement, medication, or any other substance that has been proven to slow or stop the aging process.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.