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The word drug comes from the Dutch word droog (meaning "dry"). For centuries, most drugs came from dried plants, hence the name.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).