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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
The newest statin drug, rosuvastatin, has been called a superstatin because it appears to reduce LDL cholesterol to a greater degree than the other approved statin drugs.
Asthma cases in Americans are about 75% higher today than they were in 1980.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.