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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
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More than 4.4billion prescriptions were dispensed within the United States in 2016.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Pubic lice (crabs) are usually spread through sexual contact. You cannot catch them by using a public toilet.
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Human stomach acid is strong enough to dissolve small pieces of metal such as razor blades or staples.