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Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.
As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
The first-known contraceptive was crocodile dung, used in Egypt in 2000 BC. Condoms were also reportedly used, made of animal bladders or intestines.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.