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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Many of the drugs used by neuroscientists are derived from toxic plants and venomous animals (such as snakes, spiders, snails, and puffer fish).
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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In 1864, the first barbiturate (barbituric acid) was synthesized.