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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Amphetamine poisoning can cause intravascular coagulation, circulatory collapse, rhabdomyolysis, ischemic colitis, acute psychosis, hyperthermia, respiratory distress syndrome, and pericarditis.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
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The human body produces and destroys 15 million blood cells every second.