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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
There are 20 feet of blood vessels in each square inch of human skin.