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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.