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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
It is believed that humans initially contracted crabs from gorillas about 3 million years ago from either sleeping in gorilla nests or eating the apes.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
The strongest synthetic topical retinoid drug available, tazarotene, is used to treat sun-damaged skin, acne, and psoriasis.