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In 1864, the first barbiturate (barbituric acid) was synthesized.
Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
Adolescents often feel clumsy during puberty because during this time of development, their hands and feet grow faster than their arms and legs do. The body is therefore out of proportion. One out of five adolescents actually experiences growing pains during this period.
Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.
Women are 50% to 75% more likely than men to experience an adverse drug reaction.