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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
Only one in 10 cancer deaths is caused by the primary tumor. The vast majority of cancer mortality is caused by cells breaking away from the main tumor and metastasizing to other parts of the body, such as the brain, bones, or liver.
The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.