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In 1864, the first barbiturate (barbituric acid) was synthesized.
Women are 50% to 75% more likely than men to experience an adverse drug reaction.
Street names for barbiturates include reds, red devils, yellow jackets, blue heavens, Christmas trees, and rainbows. They are commonly referred to as downers.
More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
The use of salicylates dates back 2,500 years to Hippocrates's recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.