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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.