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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.
Vital signs (blood pressure, temperature, pulse rate, respiration rate) should be taken before any drug administration. Patients should be informed not to use tobacco or caffeine at least 30 minutes before their appointment.