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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
Today, nearly 8 out of 10 pregnant women living with HIV (about 1.1 million), receive antiretrovirals.
About 3% of all pregnant women will give birth to twins, which is an increase in rate of nearly 60% since the early 1980s.