Author Question: Which is not a common step in a practice-based evidence study? a. Assemble a multidisciplinary ... (Read 191 times)

Sufayan.ah · **on:** Jul 8, 2018

Which is not a common step in a practice-based evidence study?

a. Assemble a multidisciplinary project team
b. Measure patient severity
c. Obtain patient consent
d. Collect data

Question 2

Which characteristic is an advantage that practice-based evidence studies have over RCTs?

a. Large sample sizes can be obtained easily.
b. Multiple sites are typically enrolled, resulting in greater generalizability.
c. Study efficacy is greater.
d. Multiple variables can be studied.

wshriver · **Reply #1 on:** Jul 8, 2018

Answer to Question 1

ANS: C
It is not necessary to obtain patient consent when treatment is not altered.

Answer to Question 2

ANS: C
Practice-based evidence (PBE) designs trade away the internal validity of RCTs for external validity. PBE designs have high external validity because they include virtually all patients with, or at risk for, the condition under study, as well as potential confounders that could alter treatment responses. PBE designs attempt to minimize threats to internal validity by trying to collect information on all patient variables - demographic, medical, nursing, functional, and socioeconomic - that might account for differences in outcome. By doing so, PBE designs minimize the need for compensating statistical techniques such as instrumental variables and propensity scoring to mitigate selection bias effects, unknown sources of variance, and threats to internal validity.