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In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.
It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
Excessive alcohol use costs the country approximately $235 billion every year.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.