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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.
On average, the stomach produces 2 L of hydrochloric acid per day.
Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.