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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Earwax has antimicrobial properties that reduce the viability of bacteria and fungus in the human ear.
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Parkinson's disease is both chronic and progressive. This means that it persists over a long period of time and that its symptoms grow worse over time.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.