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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
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It is widely believed that giving a daily oral dose of aspirin to heart attack patients improves their chances of survival because the aspirin blocks the formation of new blood clots.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The average office desk has 400 times more bacteria on it than a toilet.

