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Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
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In 1864, the first barbiturate (barbituric acid) was synthesized.