In myasthenia gravis, which two pulmonary function values are the ...

[Mr3Hunna]

In myasthenia gravis, which two pulmonary function values are the most sensitive in detecting respiratory muscle weakness?
 
  1. TLC and VC
  2. PImax and PEmax
  3. VC and expired volume per unit time (VE)
  4. VC and tidal volume (VT)
  a. 1 and 4 only
  b. 1 and 2 only
  c. 3 and 4 only
  d. 2 and 3 only

Question 2

Lambert-Eaton syndrome is characterized by which of the following?
 
  a. It affects mainly the limbs and eyes.
  b. Patients have a mean age of 40 years.
  c. Large-cell carcinoma is most common.
  d. It is commonly associated with small-cell lung cancer.

[nickk12214]

Answer to Question 1

ANS: B
PImax and PEmax are more sensitive markers of early respiratory muscle weakness.

Answer to Question 2

ANS: D
More than 66 of cases of Lambert-Eaton syndrome are associated with cancer. Of these can-cer-related cases, 50 are associated with small-cell carcinoma of the lung.