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The FDA recognizes 118 routes of administration.
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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Everyone has one nostril that is larger than the other.