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The familiar sounds of your heart are made by the heart's valves as they open and close.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
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Bacteria have flourished on the earth for over three billion years. They were the first life forms on the planet.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.