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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The U.S. Preventive Services Task Force recommends that all women age 65 years of age or older should be screened with bone densitometry.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.