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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
The average office desk has 400 times more bacteria on it than a toilet.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.
As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.