Answer to Question 1
Correct Answer: 1,4
Rationale 1: Pain medication given by the intravenous (IV) route will be rapidly and completely absorbed.
Rationale 2: The patient has 75 surface area burns; there may not be an area available for intramuscular injections of morphine.
Rationale 3: The patient has 75 surface area burns; there may not be an area available to place a transdermal patch.
Rationale 4: Sublingual morphine can be used as a rescue drug.
Rationale 5: The patient has 75 surface area burns; there may not be an area available for subcutaneous injections.
Answer to Question 2
Correct Answer: 1,2,3
Rationale 1: Muscles have a high blood flow, which maximizes absorption.
Rationale 2: The thick mucous layer of the stomach decreases absorption. IM drugs bypass this obstacle, resulting in increased absorption.
Rationale 3: Oral medications and food can interfere with absorption of medications. Bypassing the gastrointestinal tract will remove this possibility.
Rationale 4: Some tissues do have the ability to accumulate and store drugs. Muscle tissue is not one of these. The bone marrow, teeth, eyes, and adipose tissue have an affinity to store drugs.
Rationale 5: IM drugs do bypass the gastrointestinal tract but are not exposed to the small intestine. IM drugs are absorbed from the muscle into the blood stream.