Author Question: Which of the following potential effects on pharmacokinetics results from the reduced gastric ... (Read 55 times)

Mr.Thesaxman · **on:** Jul 23, 2018

Which of the following potential effects on pharmacokinetics results from the reduced gastric motility that occurs during pregnancy?

a. Reduced renal elimination
b. Unchanged drug distribution
c. Delayed drug absorption
d. Diminished drug biotransformation

Question 2

A patient reports that he is using a drug for an incorrect purpose. Which one of the following terms describes using a drug in this manner?

a. Adherence
b. Nonadherence
c. Misuse
d. Tolerance

Mollythedog · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: C
The most fundamental change in the gastrointestinal tract during pregnancy is the increased ab-sorption of the nutrients needed by the developing fetus. Gastric motility and tone are decreased during pregnancy because of the smooth muscle relaxation effects of progesterone. These chang-es result in delayed gastric emptying, prolonged drug absorption, and lower peak drug concentra-tions.

Answer to Question 2

ANS: C
Drug misuse, the use of a drug for the wrong purpose, is often the result of inaccurate self-diagnosis. In addition, the administration of a drug in situations in which contraindications are misunderstood or not recognized contributes to drug misuse.