Author Question: A client is receiving oxybutynin for treatment of overactive bladder. The client also takes ... (Read 81 times)

kwoodring · **on:** Jul 23, 2018

A client is receiving oxybutynin for treatment of overactive bladder. The client also takes haloperidol (Haldol) as an antipsychotic agent. What effect of the interaction of these two drugs should the nurse observe for in the client?

A) Decreased effect of the antipsychotic drug
B) Increased risk for bleeding
C) Lowered plasma concentrations
D) Increased effect of the antispasmodic drug

Question 2

A nurse is providing care to a client diagnosed with benign prostatic hypertrophy. The nurse understands that which of the following drugs inhibit the conversion of testosterone into 5-alpha-dihydrotestosterone (DHT),

resulting in a decrease in prostate gland size? Select all that apply.

A) Terazosin (Hytrin)
B) Finasteride (Proscar)
C) Methyltestosterone (Testred)
D) Dutasteride (Avodart)
E) Doxazosin (Cardura)

katieost · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Ans: A
Feedback:
The nurse should observe for decreased effectiveness of the antipsychotic drug in the client as the effect of the interaction of the antispasmodic drug and haloperidol. Increased risk for bleeding results from the interaction of oral anticoagulants with anti-infective drugs. Increased effect of the antispasmodic drug occurs with the interaction of an antispasmodic drug with a tricyclic antidepressant. Plasma concentrations are lowered due to the interaction of fosfomycin, which is an anti-infective, with metoclopramide, which is used to relieve gastric upset.

Answer to Question 2

Ans: B, D
Feedback:
Finasteride (Proscar) and dutasteride (Avodart) inhibit the conversion of testosterone into 5-alpha-dihydrotestosterone (DHT), which results in a decrease in prostate gland size, making them useful in the treatment of benign prostatic hypertrophy.