Author Question: The mechanism of action of azole systemic antifungal agents is to 1. interfere with the synthesis ... (Read 39 times)

naturalchemist · **on:** Jul 23, 2018

The mechanism of action of azole systemic antifungal agents is to

1. interfere with the synthesis of ergosterol in the fungal cell membrane.
2. concentrate in the food source of the infecting agent.
3. bind to steroids in the fungal cell membrane.
4. kill fungal growth.

Question 2

A patient has been diagnosed with trichomoniasis. The nurse would give which medication without questioning the prescription

1. Praziquantel (Biltricide.
2. Chloroquine (Aralen).
3. Nitazoxanide (Alinia).
4. Metronidazole (Flagyl).

phuda · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

1
Rationale 1: Azole systemic antifungal agents interfere with the synthesis of ergosterol in the fungal cell membrane, causing them to become permeable.
Rationale 2: Antimalaria drugs concentrate in the food source of the infecting agent.
Rationale 3: Superficial fungal agents bind to sterols in the fungal cell membrane, allowing leakage of contents.
Rationale 4: None of these agents will kill the fungal growth.
Global Rationale: Systemic antifungal agents interfere with the synthesis of ergosterol in the fungal cell membrane, causing them to become permeable. Antimalaria drugs concentrate in the food source of the infecting agent. Superficial fungal agents bind to sterols in the fungal cell membrane, allowing leakage of contents.
None of these agents will kill the fungal growth.

Answer to Question 2

4
Rationale 1: Praziquantel (Biltricide) is an anthelmintic effective against flatworms.
Rationale 2: Chloroquine (Aralen) is an antimalarial drug.
Rationale 3: Nitazoxanide (Alinia) is used to treat diarrhea caused by giardiasis in children.
Rationale 4: Metronidazole is the drug of choice for both giardiasis and trichomoniasis due to Trichomonas vaginalis.
Global Rationale: Metronidazole is the drug of choice for both giardiasis and trichomoniasis due to Trichomonas vaginalis. Praziquantel (Biltricide) is an anthelmintic effective against flatworms. Chloroquine (Aralen) is an antimalarial drug. Nitazoxanide (Alinia) is used to treat diarrhea caused by giardiasis in children.