Answer to Question 1
Correct Answer: 3
Rationale 1: The integumentary system is not affected with orlistat.
Rationale 2: Orlistat (Alli) does not influence neurological function.
Rationale 3: Orlistat should be used with caution in clients with cholestasis because the drug inhibits gallbladder contraction.
Rationale 4: No sensory deficit is associated with this drug.
Global Rationale: Orlistat should be used with caution in clients with cholestasis because the drug inhibits gallbladder contraction. The integumentary system, sensory system, and neurological systems are not affected by this drug.
Answer to Question 2
Correct Answer: 2
Rationale 1: Orlistat is not contraindicated in individuals with asthma.
Rationale 2: Hypothyroid-related weight gain should not be treated with orlistat.
Rationale 3: Diabetes is not a contraindication for this drug therapy.
Rationale 4: Presbyopia is not worsened by taking orlistat.
Global Rationale: Orlistat is contraindicated for patients who have a known cause of obesity, such as hypothyroidism, and in patients with severe malabsorption disorders. Asthma, diabetes, and presbyopia are not contraindications for orlistat therapy.