Answer to Question 1
Correct Answer: 2
Rationale 1: This statement does not describe a particular model.
Rationale 2: This statement describes the cell kill hypothesis.
Rationale 3: This statement describes staging.
Rationale 4: This statement describes grading.
Global Rationale: The cell kill hypothesis is a theoretical model that predicts the ability of antineoplastic drugs to eliminate cancer cells. This hypothesis predicts that a drug will kill a certain percentage, rather than a constant number, of cancer cells. It does not predict the number of normal cells that will be affected. Staging gauges invasiveness. Grading compares cancerous cells to normal cells.
Answer to Question 2
Correct Answer: 1,2,4
Rationale 1: Staging does determine the location of the cancer.
Rationale 2: When solid tumors are staged, diagnostic testing also determines the involvement of the lymph nodes.
Rationale 3: Once a cancer is staged, the level does not change even if the cancer progresses.
Rationale 4: Clients with cancer at a lower stage have a better prognosis than those who are diagnosed at a higher stage.
Rationale 5: This describes cancer grading, not cancer staging.
Global Rationale: During the staging of solid tumors, diagnostic testing determines the size of the tumor, whether the tumor has invaded surrounding tissue, the involvement of lymph nodes, and the presence or absence of metastasis. Once a cancer is staged, the level does not change even if the cancer progresses. Clients with cancer at a lower stage have a better prognosis than those who are diagnosed at a higher stage. Comparison of cells occurs in grading, not staging.