Author Question: All six major classes of drugs used to manage HIV infection have the ability to: 1. Prevent the ... (Read 79 times)

ec501234 · **on:** Jul 23, 2018

All six major classes of drugs used to manage HIV infection have the ability to:

1. Prevent the virus from entering the host cell.
2. Destroy the cell walls of the virus.
3. Inhibit enzymes that are necessary for viral replication.
4. Promote cell division only in uninfected cells.

Question 2

A client is started on efavirenz, a NNRTI. Which medication should the nurse question before giving it with efavirenz?

1. Diazepam
2. Penicillin
3. Ibuprofen
4. Diphenhydramine

angrybirds13579 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 3
Rationale 1: The six major classes of drugs do not prevent the virus from entering the host cell.
Rationale 2: The six major classes of drugs do not destroy cell walls of the virus.
Rationale 3: All six major classes of drugs used to manage HIV infection inhibit enzymes necessary for viral replication.
Rationale 4: None of the six major classes of drugs promotes cell division in uninfected cells.
Global Rationale: Because reverse transcriptase is a viral enzyme not found in human cells, it has been possible to design drugs with the ability to selectively inhibit viral replication. These drugs do not prevent the virus from entering the host cell, do not destroy viral cell walls, and do not promote cell division in uninfected cells.

Answer to Question 2

Correct Answer: 1
Rationale 1: The CNS adverse effects of efavirenz are worsened if the client takes psychotropic drugs, such as diazepam.
Rationale 2: Penicillin and efavirenz do not have significant drug interactions.
Rationale 3: Ibuprofen and efavirenz do not have significant drug interactions.
Rationale 4: Diphenhydramine and efavirenz do not have significant drug interactions.
Global Rationale: The CNS adverse effects of efavirenz are worsened if the client takes psychotropic drugs, such as diazepam. There are not significant drug interactions with penicillin, ibuprofen, or diphenhydramine.