A client with AIDS is suffering from a systemic fungal infection. ...

[ssal]

A client with AIDS is suffering from a systemic fungal infection. The nurse anticipates that the drug of choice for this client will be:
 
  1. fluconazole.
  2. amphotericin B.
  3. nystatin.
  4. griseofulvin.

Question 2

The nurse is caring for a client who has both a superficial and a systemic fungal infection. Which drugs can be used to treat both infections?
 
  Standard Text: Select all that apply.
  1. Ketoconazole (Nizoral)
  2. Voriconazole (Vfend)
  3. Itraconazole (Sporanox)
  4. Fluconazole (Diflucan)
  5. Nystatin (Mycostatin)

[allisonblackmore]

Answer to Question 1

Correct Answer: 2
Rationale 1: Fluconazole is for simple fungal infections.
Rationale 2: The drug of choice for these disorders is amphotericin B.
Rationale 3: Nystatin is for simple fungal infections such as Candida.
Rationale 4: Griseofulvin is for superficial fungal infections.
Global Rationale: The AIDS epidemic, however, resulted in the frequent clinical occurrence of previously rare mycoses, such as cryptococcosis and coccidioidomycosis. Pharmacologic options for serious systemic mycoses are limited. Amphotericin B (Fungizone) has been the traditional drug of choice for systemic fungal infections since the 1960s. Fluconazole is for simple fungal infections. Nystatin is for simple fungal infections such as Candida. Griseofulvin is for superficial fungal infections.

Answer to Question 2

Correct Answer: 1,2,3,4
Rationale 1: Nizoral can be used to treat both types of infections.
Rationale 2: Vfend can be used to treat both types of infections.
Rationale 3: Sporanox can be used to treat both types of infections.
Rationale 4: Diflucan can be used to treat both types of infections.
Rationale 5: Nystatin is used to treat superficial infections.
Global Rationale: Fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil) and voriconazole (Vfend) are used for both systemic and topical infections. Nystatin is used to treat superficial infections.

[ssal]

Thanks

[allisonblackmore]

Welcome