Answer to Question 1
Correct Answer: 1,2,3
Rationale 1: Penicillin inhibits bacterial cell wall synthesis.
Rationale 2: Penicillin inhibits cell wall synthesis, resulting in the cell absorbing water and lysing.
Rationale 3: Binding to specific proteins disrupts the cell's ability to build a wall.
Rationale 4: Interference of the transfer of RNA occurs during the inhibition of protein synthesis by the aminoglycosides, tetracyclines, macrolides, and oxazolidinones.
Rationale 5: The disruption of the plasma membrane is the mechanism of action of azoles and polyenes.
Answer to Question 2
Correct Answer: 1,2,3
Rationale 1: Streptococci can cause meningitis in children.
Rationale 2: Escherichia coli can cause meningitis in children.
Rationale 3: Haemophilus influenzae can cause meningitis in children.
Rationale 4: Rickettsia rickettsii is the organism responsible for Rocky Mountain spotted fever.
Rationale 5: Shigella is an organism responsible for dysentery.
Global Rationale: Streptococci, Escherichia coli, and Haemophilus influenzae can cause meningitis in children.