Author Question: A client is being treated with dornase alfa (Pulmozyme). The nurse anticipates that the client is ... (Read 22 times)

sarasara · **on:** Jul 23, 2018

A client is being treated with dornase alfa (Pulmozyme). The nurse anticipates that the client is most likely to experience which cluster of adverse effects?

1. Headache, nasal stuffiness, and earaches
2. Nausea, vomiting, and diarrhea
3. Epigastric pain, belching, and flatulence
4. Sore throat, conjunctivitis, and hoarseness

Question 2

The nurse is assisting with the administration of an acetylcysteine (Mucomyst) nebulizer treatment by mask. What warning to the client is essential prior to the start of the treatment?

1. Tell us right away if your fingers start to tingle.
2. This treatment does not smell very good.
3. This treatment may make you feel dizzy.
4. Tell us right away if you develop chest pain.

carojassy25 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 4
Rationale 1: Headache, nasal stuffiness, and earache are not common adverse effects of Pulmozyme.
Rationale 2: Nausea, vomiting, and diarrhea are not common adverse effects of Pulmozyme.
Rationale 3: Epigastric pain, belching, and flatulence are not common adverseeffects of Pulmozyme.
Rationale 4: The most common adverse effects of Pulmozyme are chest pain, hoarseness, sore throat, and conjunctivitis.
Global Rationale: Dornase alfa (Pulmozyme), is an enzyme that was approved in 1993 for the management of thick bronchial secretions in patients with cystic fibrosis. Dornase alfa breaks down deoxyribonucleic acid (DNA) molecules in the mucus, causing it to become less viscous. It is administered by the oral inhalation route. Adverse effects include chest pain, conjunctivitis, hoarseness, and pharyngitis. The remaining adverse effects are not assocated with Pulmozyme.

Answer to Question 2

Correct Answer: 2
Rationale 1: Mucomyst does not cause tingling.
Rationale 2: Mucomyst smells like rotten eggs. The odor bothers some more than others.
Rationale 3: Mucomyst does not cause dizziness.
Rationale 4: Mucomyst does not trigger chest pain.
Global Rationale: Acetylcysteine has a very unpleasant odor and can cause nausea and vomiting. Local irritation and stickiness on the face are also noted. It does not cause tingling, dizziness, or chest pain.