Drug half-life for an older child can be shortened because of ...

[maegan_martin]

Drug half-life for an older child can be shortened because of increased metabolic rate. How does this affect the drug dose for older children versus that for adults?
 
  a. It is increased because of drug metabolism.
  b. It is decreased because of drug metabolism.
  c. It is decreased because of an increased half-life.
  d. It is the same as that for adults.

Question 2

The client is being treated for hypertension. He tells the nurse that he has been taking Yohimbe. The nurse anticipates a(n) _____ drug effect and _____ hypertension as a result of this self-medication.
 
  a. decreased; decreased
  b. decreased; increased
  c. increased; decreased
  d. increased; increased

[jomama]

Answer to Question 1

ANS: A
With a shorter half-life, more of the drug is eliminated quickly. This requires a higher dose of the medication.

Answer to Question 2

ANS: B
The client who is hypertensive will likely experience a decreased effect from his antihypertensive medication and an increase in his hypertension if he is simultaneously taking Yohimbe.

[maegan_martin]

Gracias!

[marict]

Thanks for the timely response, appreciate it