The nurse is preparing to administer clarithromycin to a patient. ...

[EY67]

The nurse is preparing to administer clarithromycin to a patient. When performing a medication history, the nurse learns that the patient takes warfarin to treat atrial fibrillation. The nurse will perform which action?
 
  a. Ask the provider if azithromycin may be used instead of clarithromycin.
  b. Obtain an order for continuous cardiovascular monitoring.
  c. Request an order for periodic serum warfarin levels.
  d. Withhold the clarithromycin and notify the provider.

Question 2

A female patient who is allergic to penicillin will begin taking an antibiotic to treat a lower respiratory tract infection.
 
  The patient tells the nurse that she almost always develops a vaginal yeast infection when she takes antibiotics and that she will take fluconazole (Diflucan) with the antibiotic being prescribed. Which macrolide order would the nurse question for this patient?
  a. Azithromycin (Zithromax)
  b. Clarithromycin (Biaxin)
  c. Erythromycin (E-Mycin)
  d. Fidaxomicin (Dificid)

[ttt030911]

Answer to Question 1

ANS: C
Macrolides can increase serum levels of other drugs such as warfarin. If these drugs are used with macrolides, serum drug levels should be monitored. All macrolides have this drug interaction. Cardiovascular monitoring is not indicated. The drug may be given as long as serum drug levels are monitored.

Answer to Question 2

ANS: C
When erythromycin is given concurrently with fluconazole, erythromycin blood concentration and the risk of sudden cardiac death increase.

[EY67]

Both answers were spot on, thank you once again

[ttt030911]

Great! Please up vote