A patient is to be started on adalimumab (Humira) for management ...

[MirandaLo]

A patient is to be started on adalimumab (Humira) for management of rheumatoid arthritis. Which of the following statements by the patient demonstrates accurate knowledge about the drug?
 
  a. My husband will be giving me intramuscular injections of the medication in my lateral thighs.
  b. I have been taught how to administer the medication to myself in the fatty tis-sues of my anterior thighs and abdomen.
  c. The drug must be stored in a warm place.
  d. The drug is more likely to cause allergic reactions when administered orally.

Question 2

The spouse of a patient with advanced Alzheimer's disease confides to the nurse that the patient's wandering, pacing, and agitation seems to get worse in the evening. The nurse correctly explains this phenomenon to the spouse as
 
  a. evening psychosis.
  b. sundowner's syndrome.
  c. drug toxicity.
  d. new onset of psychosis.

[ky860224]

Answer to Question 1

B
Adalimumab is administered subcutaneously in the anterior thighs or abdomen by the nurse, pa-tient, or caregiver.
Adalimumab is for subcutaneous administration only.
Adalimumab should be stored cold at 2 to 8 C (36 to 46 F).
Adalimumab is not available for oral administration.

Answer to Question 2

B
Between 70 and 90 of patients with Alzheimer's disease develop wandering, pacing, agita-tion, and screaming. Symptoms may intensify in the evening, a phenomenon known as sun-downer's syndrome.
Evening psychosis is not a phenomenon associated with Alzheimer's disease.
The phenomena reported are symptoms of Alzheimer's disease and are not related to drug toxic-ity.
New-onset psychosis is not appropriate, and the nurse could not offer that diagnosis.