« previous next »

Author Question: Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it cannot ... (Read 13 times)

maychende

  • Hero Member
  • *****
  • Posts: 556
on: Jul 23, 2018
Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it cannot be used to treat a friend's illness. Which statement by the nurse is correct?
 
  a. A drug at this stage of development can be used only in patients with serious dis-ease.
  b. At this stage of drug development, the safety and usefulness of the medication is unknown.
  c. Clinical trials must be completed to make sure the drug is safe to use in humans.
  d. Until postmarketing surveillance data are available, the drug cannot be used.

Question 2

A child will begin taking methylphenidate Ritalin for attention-deficit/hyperactivity disorder. Important baseline information about this patient will include:
 
  a. results of an electrocardiogram (ECG).
  b. family history of psychosis.
  c. height and weight.
  d. renal function.


potomatos

  • Sr. Member
  • ****
  • Posts: 338
Reply #1 on: Jul 23, 2018
Answer to Question 1

B
Preclinical testing must be completed before drugs can be tested in humans. In this stage, drugs are evaluated for toxicities, pharmacokinetic properties, and potentially useful effects. Some drugs can be used in patients before completion of Phase III studies, but this is after preclinical testing is complete. Clinical trials proceed in stages, and each stage has guidelines defining how a new drug may be used and which patients may receive it. Postmarketing surveillance takes place after a drug is in general use.

Answer to Question 2

C
Side effects of methylphenidate include a reduced appetite, and children taking these drugs should be monitored for growth suppression. Baseline height and weight measurements help with this ongoing assessment. The value of an ECG for children has not been proven, except when known heart disease is a factor. Excessive use of stimulants can produce a state of psychosis but is not related to the family history. Renal function tests are not indicated.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question

maychende

  • Hero Member
  • *****
  • Posts: 556
Reply #2 on: Jul 23, 2018
Both answers were spot on, thank you once again


potomatos

  • Sr. Member
  • ****
  • Posts: 338
Reply #3 on: Jul 23, 2018
Great! Please up vote :D


« previous next »
 

Did you know?

As of mid-2016, 18.2 million people were receiving advanced retroviral therapy (ART) worldwide. This represents between 43–50% of the 34–39.8 million people living with HIV.

Did you know?

Pubic lice (crabs) are usually spread through sexual contact. You cannot catch them by using a public toilet.

Did you know?

Vaccines cause herd immunity. If the majority of people in a community have been vaccinated against a disease, an unvaccinated person is less likely to get the disease since others are less likely to become sick from it and spread the disease.

Did you know?

This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.

Did you know?

In the ancient and medieval periods, dysentery killed about ? of all babies before they reach 12 months of age. The disease was transferred through contaminated drinking water, because there was no way to adequately dispose of sewage, which contaminated the water.

Nurse-patient interaction; nonverbal communication Nurse-patient interaction; nonverbal communication
Barriers that a drug administered by the oral route must cross before interacting with a target ... Barriers that a drug administered by the oral route must cross before interacting with a target ...
Drug inhibition of folic acid metabolism. Drugs inhibit multiple steps in the metabolic pathway ... Drug inhibition of folic acid metabolism. Drugs inhibit multiple steps in the metabolic pathway ...
Drug Administration Guidelines with Enteral Feedings Drug Administration Guidelines with Enteral Feedings
The nurse conveys attentive listening through a posture of involvement The nurse conveys attentive listening through a posture of involvement
The Drug Development Process The Drug Development Process
Video: Primary and secondary response to infection

For a complete list of videos, visit our video library