« previous next »

Author Question: Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it cannot ... (Read 34 times)

maychende

  • Hero Member
  • *****
  • Posts: 556
on: Jul 23, 2018
Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it cannot be used to treat a friend's illness. Which statement by the nurse is correct?
 
  a. A drug at this stage of development can be used only in patients with serious dis-ease.
  b. At this stage of drug development, the safety and usefulness of the medication is unknown.
  c. Clinical trials must be completed to make sure the drug is safe to use in humans.
  d. Until postmarketing surveillance data are available, the drug cannot be used.

Question 2

A child will begin taking methylphenidate Ritalin for attention-deficit/hyperactivity disorder. Important baseline information about this patient will include:
 
  a. results of an electrocardiogram (ECG).
  b. family history of psychosis.
  c. height and weight.
  d. renal function.


potomatos

  • Sr. Member
  • ****
  • Posts: 338
Reply #1 on: Jul 23, 2018
Answer to Question 1

B
Preclinical testing must be completed before drugs can be tested in humans. In this stage, drugs are evaluated for toxicities, pharmacokinetic properties, and potentially useful effects. Some drugs can be used in patients before completion of Phase III studies, but this is after preclinical testing is complete. Clinical trials proceed in stages, and each stage has guidelines defining how a new drug may be used and which patients may receive it. Postmarketing surveillance takes place after a drug is in general use.

Answer to Question 2

C
Side effects of methylphenidate include a reduced appetite, and children taking these drugs should be monitored for growth suppression. Baseline height and weight measurements help with this ongoing assessment. The value of an ECG for children has not been proven, except when known heart disease is a factor. Excessive use of stimulants can produce a state of psychosis but is not related to the family history. Renal function tests are not indicated.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question

maychende

  • Hero Member
  • *****
  • Posts: 556
Reply #2 on: Jul 23, 2018
Both answers were spot on, thank you once again


potomatos

  • Sr. Member
  • ****
  • Posts: 338
Reply #3 on: Jul 23, 2018
Great! Please up vote :D


« previous next »
 

Did you know?

For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.

Did you know?

Despite claims by manufacturers, the supplement known as Ginkgo biloba was shown in a study of more than 3,000 participants to be ineffective in reducing development of dementia and Alzheimer’s disease in older people.

Did you know?

To prove that stomach ulcers were caused by bacteria and not by stress, a researcher consumed an entire laboratory beaker full of bacterial culture. After this, he did indeed develop stomach ulcers, and won the Nobel Prize for his discovery.

Did you know?

More than one-third of adult Americans are obese. Diseases that kill the largest number of people annually, such as heart disease, cancer, diabetes, stroke, and hypertension, can be attributed to diet.

Did you know?

As many as 20% of Americans have been infected by the fungus known as Histoplasmosis. While most people are asymptomatic or only have slight symptoms, infection can progress to a rapid and potentially fatal superinfection.

The tone of the nurse-patient introduction sets the stage for the patient interview and patient care The tone of the nurse-patient introduction sets the stage for the patient interview and patient care
U.S. Drug Schedules and Examples U.S. Drug Schedules and Examples
Hookup for testing fuel-pump current draw on any vehicle equipped with a fuel-pump relay. Hookup for testing fuel-pump current draw on any vehicle equipped with a fuel-pump relay.
Some mechanisms of agonistic and antagonistic drug effects. Some mechanisms of agonistic and antagonistic drug effects.
Insurgencies and Drug Trafficking Insurgencies and Drug Trafficking
Drug Approval Stages Drug Approval Stages
Video: Neural Reflex Arc Animation

For a complete list of videos, visit our video library