Author Question: Why do COX-2 inhibitors increase the risk for cardiovascular problems? (Select all that apply.) ... (Read 52 times)

EAugust · **on:** Jul 23, 2018

Why do COX-2 inhibitors increase the risk for cardiovascular problems? (Select all that apply.)

A) Vasoconstriction is blocked.
B) Vasodilation is blocked.
C) Platelet clumping is blocked.
D) Water and sodium balance is altered.
E) Gastrointestinal (GI) integrity is altered.

Question 2

A researcher is studying chromosomal disorders. What part of the human cell would the researcher be interested in studying?

A) Cytoplasm
B) Membrane
C) Nucleus
D) Organelles

DHRUVSHAH · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

B, C
Feedback:
Recent studies suggest that COX-2 inhibitors may block some protective responses in the body, such as vasodilation and inhibited platelet clumping, which is protective if vessel narrowing or blockage occurs. Blocking this effect could lead to cardiovascular problems. Vasoconstriction is not blocked, water and sodium balance is not altered, and GI integrity is not impacted by COX-2 inhibitors but can be impacted by COX-1 inhibitors.

Answer to Question 2

C
Feedback:
The nucleus of a cell contains all of the genetic material that is necessary for cell reproduction. The nucleus also contains genes or sequences of deoxyribonucleic acid (DNA). Genes are responsible for the formation of messenger ribonucleic acid (mRNA) and transcription RNA, which are involved in production of proteins unique to the cells. This is the area where chromosomal disorders originate. The cell cytoplasm lies within the cell membrane and is the site of activities of cellular metabolism and special cellular functions. The organelles are contained within the cytoplasm and are structures with specific functions. They include the mitochondria, endoplasmic reticulum, free ribosomes, Golgi apparatus, and lysosomes. The membrane is a thin barrier, which separates the intracellular fluid from the extracellular fluid and is essential for cellular integrity; it also maintains cell homeostasis.