A patient who has been taking cyclosporine to prevent rejection ...

[Garrulous]

A patient who has been taking cyclosporine to prevent rejection of a kidney transplant has had diltiazem ordered. Why would the nurse question this order?
 
  A) Serious diltiazem toxicity could occur.
  B) The combination may result in elevated or even toxic cyclosporine levels.
  C) The combination could lead to kidney rejection.
  D) A kidney recipient would not effectively excrete the diltiazem.

Question 2

The home care nurse administers oral morphine to the patient with cancer pain. When will the nurse expect this medication to reach peak activity?
 
  A) 10 minutes
  B) 30 minutes
  C) 45 minutes
  D) 60 minutes

[Dunkey]

Answer to Question 1

B
Feedback:
Potentially serious adverse effects to keep in mind include increased serum levels and toxicity of cyclosporine if they are taken with diltiazem. This combination is not associated with diltiazem toxicity. A functioning implanted kidney should still excrete diltiazem. This drug would not cause rejection of a transplanted kidney.

Answer to Question 2

D
Feedback:
With oral administration, peak activity occurs in about 60 minutes. The duration of action is 5 to 7 hours.

[Garrulous]

YES! Correct, THANKS for helping me on my review

[adf223]

Thanks for the timely response, appreciate it