Author Question: Baclofen is a prototype drug for the centrally acting skeletal muscle relaxants. What adverse ... (Read 46 times)

londonang · **on:** Jul 23, 2018

Baclofen is a prototype drug for the centrally acting skeletal muscle relaxants. What adverse effects do drugs in this class have? (Select all that apply.)

A) Coronary artery disease
B) Hypotension
C) Urinary frequency
D) Dizziness
E) Bone marrow suppression

Question 2

The nurse determines a child's body surface area is 0.4 m2 and the average adult dosage of the medication is 500 mg. The medication is supplied in liquid form with 500mg/5 mL. How many milliliter will the nurse administer?

A) 3.46 mL
B) 1.73 mL
C) 0.5 mL
D) 12 mL

hanadaa · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

B, C, D
Feedback:
Adverse effects include transient drowsiness, dizziness, weakness, fatigue, constipation, headache, insomnia, hypotension, nausea, and urinary frequency. Bone marrow suppression and coronary artery disease are not associated with therapy involving these drugs.

Answer to Question 2

A
Feedback:
The formula for calculating the child's dose using body surface area is surface area in m2 divided by 1.73 and then multiplied by adult dosage. Using the information supplied in this problem (0.4 1.73) 500 mg = 346 mg. Using the ratio and proportion method, 500 mg/5 mL = 346 mg/X mL; cross-multiplying yields 3.46 mL for the nurse to administer.