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Author Question: A patient with Parkinson's disease has been prescribed rasagiline. When educating this patient on ... (Read 74 times)

frankwu

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on: Jul 23, 2018
A patient with Parkinson's disease has been prescribed rasagiline. When educating this patient on this medication, which herbal supplement has the potential to produce hyperpyrexia and death with rasagiline?
 
  A) Ginger
  B) Dextromethorphan
  C) Garlic
  D) St. John's wort

Question 2

Epinephrine is being considered in the treatment of an adult hospital patient. In anticipation, the nurse has reviewed the patient's current medication regimen.
 
  The presence of a drug from which of the following drug categories would contraindicate the safe use of epinephrine? A) Potassium-wasting diuretics
  B) Sulfonamide antibiotics
  C) Selective serotonin reuptake inhibitors (SSRIs)
  D) Monoamine oxidase (MAO) inhibitors


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catron30

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Reply #1 on: Jul 23, 2018
Answer to Question 1

D
Feedback:
Rasagiline administered with the herbal supplement St. John's wort will enhance the stimulation of serotonergic receptors to cause hyperpyrexia and death. Dextromethorphan can produce the same reaction but is not an herbal supplement. Ginger and garlic are herbal supplements but will not produce hyperpyrexia and death.

Answer to Question 2

D
Feedback:
It is essential not to give MAO inhibitors with adrenergic drugs because the combination may cause death. Use of adrenergics with diuretics, SSRIs, or sulfa antibiotics is not necessarily contraindicated.


frankwu

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Reply 2 on: Jul 23, 2018
Thanks for the timely response, appreciate it

ttt030911

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Reply 3 on: Yesterday
Wow, this really help

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