A nurse has administered a dose of a drug that is known to be ...

[Zoey63294]

A nurse has administered a dose of a drug that is known to be highly protein bound. What are the implications of this characteristic?
 
  A) The patient must consume adequate protein in order to achieve a therapeutic effect.
  B) The molecules of the drug that are bound to protein are inactive.
  C) Increased levels of serum protein will increase the effect of the drug.
  D) Each molecule of the drug must bind to a protein molecule to become effective.

Question 2

A patient is scheduled to receive an immunization. In which of the following patients is the administration of live vaccine contraindicated?
 
  A) Patient with renal insufficiency
  B) Patient with hepatic failure
  C) Patient taking steroid therapy
  D) Patient over the age of 65 years

[uniquea123]

Answer to Question 1

B
Feedback:
Drug molecules bound to plasma proteins are pharmacologically inactive because the large size of the complex prevents their leaving the bloodstream through the small openings in capillary walls and reaching their sites of action, metabolism, and excretion. Only the free or unbound portion of a drug acts on body cells. The patient's protein intake or levels of protein are not normally relevant.

Answer to Question 2

C

[Zoey63294]

Thank you!

[uniquea123]

Always glad to help...