A patient is receiving chloroquine (Aralen) for extraintestinal ...

[future617RT]

A patient is receiving chloroquine (Aralen) for extraintestinal amebiasis. Which of the following medications should be administered with chloroquine?
 
  A) Iodoquinol (Yodoxin)
  B) Metronidazole (Flagyl)
  C) Metyrosine (Demser)
  D) Carbamazepine (Tegretol)

Question 2

The administration of benzene hexachloride (Lindane) for the treatment of scabies is applied in small quantities. What is the rationale for instructing the patient to apply the medication in small quantities?
 
  A) Excessive applications will lead to central nervous system toxicity.
  B) Excessive applications will cause irritation, rash, and inflammation.
  C) Excessive applications will cause headaches, dizziness, and diarrhea.
  D) Excessive applications will lead to anorexia and cachexia.

[kswal303]

Answer to Question 1

B
Feedback:
Chloroquine is used mainly for its antimalarial effects. When used as an amebicide, the drug is effective in extraintestinal amebiasis, but usually ineffective in intestinal amebiasis. Treatment is usually combined with an intestinal amebicide. Metronidazole is an intestinal amebicide. Iodoquinol is an iodine compound that acts against amebae in the intestinal lumen. Metyrosine is an enzyme inhibitor. Carbamazepine is an antiseizure medication.

Answer to Question 2

A
Feedback:
Lindane is applied topically, and substantial amounts are absorbed through intact skin. Central nervous toxicity has been reported with excessive use. The application of Lindane will not cause irritation, rash, or inflammation. The application of Lindane will not cause headaches, dizziness, or diarrhea. The application of Lindane will not lead to anorexia or cachexia.

[future617RT]

Gracias!

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Thanks for the timely response, appreciate it